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Here are the 49 US AI startups that have raised $100M or more in 2025
In 2025, 49 U.S. AI startups have raised over $100M in funding, matching last year's record. Notably, several companies secured multiple mega-rounds, with 2025 exceeding 2024 in terms of companies raising above $100M. Highlights include Anysphere raising $2.3B and Hippocratic AI obtaining $126M, underlining the sustained growth and investment in the AI sector.
Key points
- 2025 matches 2024 in the number of startups raising over $100M in funding.
- Anysphere secured $2.3B, making it one of the largest funding rounds this year.
- Hippocratic AI raised $126M, emphasizing strong interest in healthcare AI.
- Seven companies raised rounds of $1 billion or more, showcasing heightened investor confidence.
- More companies raised multiple rounds over $100M in 2025 compared to 2024.
Why it matters
- The surge in funding reflects ongoing trends in AI technology and its applications across various industries.
- 2024 and 2025 funding rounds mirror the historical growth observed in the tech sector post-pandemic, especially in AI.
- AI startups are transforming sectors such as healthcare, legal tech, and infrastructure, echoing 2025's focus on innovation.
The impressive fundraising in 2025 highlights an ongoing robust investment landscape in AI, suggesting its pivotal role in future technological advancements and market competitiveness.